1201065-88-4Relevant academic research and scientific papers
A new process of multicomponent Povarov reaction-aerobic dehydrogenation: synthesis of polysubstituted quinolines
Guchhait, Sankar K.,Jadeja, Khyati,Madaan, Chetna
, p. 6861 - 6865 (2009)
A new domino process of three-component Povarov reaction and aerobic dehydrogenation was developed toward the synthesis of polysubstituted quinolines. 2,4-Disubstituted-8-nitroquinolines, which are important precursors for the synthesis of antimalarial primaquine drug-like molecules, were prepared conveniently by this method in moderate to good yields. Br?nsted acid (HClO4)-modified montmorillonite was found to be a crucial catalyst in promoting the procedure.
