1201072-25-4Relevant academic research and scientific papers
Rhodium(I)-catalyzed [4+1] cycloaddition reactions of α, βunsaturated imines with terminal alkynes for the preparation of pyrrole derivatives
Mizuno, Akio,Kusama, Hiroyuki,Iwasawa, Nobuharu
supporting information; experimental part, p. 8318 - 8320 (2010/02/27)
Rhodium vinylidene intermediates are characteristic for the title reaction (see scheme; coe = cyclooctene, cy = cyclohexyl). This reaction proceeds by the nucleophilic addition of the nitrogen atom of the imine to the rhodium vinylidene complex to give a zwitterionic intermediate, which undergoes intramolecular cyclization to afford the corresponding pyrrole.
