1201179-46-5

Basic information

• Product Name: 3,5-diamino-6-chloro-pyrazine-2-carboxylic acid {(S)-2-[3-(4-methoxy-phenyl)-propylamino]-pentyl}-amide hydrochloride
• Synonyms: 3,5-diamino-6-chloro-pyrazine-2-carboxylic acid {(S)-2-[3-(4-methoxy-phenyl)-propylamino]-pentyl}-amide hydrochloride
• CAS NO: 1201179-46-5
• Molecular Weight: 457.403
• Mol File: 1201179-46-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,5-diamino-6-chloro-pyrazine-2-carboxylic acid {(S)-2-[3-(4-methoxy-phenyl)-propylamino]-pentyl}-amide hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-diamino-6-chloro-pyrazine-2-carboxylic acid {(S)-2-[3-(4-methoxy-phenyl)-propylamino]-pentyl}-amide hydrochloride(1201179-46-5)
• EPA Substance Registry System: 3,5-diamino-6-chloro-pyrazine-2-carboxylic acid {(S)-2-[3-(4-methoxy-phenyl)-propylamino]-pentyl}-amide hydrochloride(1201179-46-5)

Safety Data

• Hazardous Substances Data: 1201179-46-5(Hazardous Substances Data)

Upstream product

• 116611-57-5 tert-butyl [(1S)-1-(hydroxymethyl)butyl]carbamate 
• 1196038-52-4 ((S)-1-{[(3,5-diamino-6-chloro-pyrazine-2-carbonyl)-amino]-methyl}-butyl)-carbamic acid tert-butyl ester 
• 1196038-50-2 [(S)-1-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-butyl]-carbamic acid tert-butyl ester 
• 1196038-51-3 ((S)-1-aminomethyl-butyl)-carbamic acid tert-butyl ester 
• 1201179-45-4 3,5-diamino-6-chloro-pyrazine-2-carboxylic acid ((S)-2-aminopentyl)-amide hydrochloride 
• 20401-88-1 3-(4-methoxyphenyl)propional 

Relevant articles and documents

3,5-DIAMINO-6-CHLORO-PYRAZINE-2-CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS EPITHELIAL SODIUM CHANNEL BLOCKERS FOR THE TREATMENT OF ARWAY DISEASES

A compound of Formula (I) in free or salt or solvate form, where R1, R2, R3, R4, R5, R6, R7, R8 and R9 have the meanings as indicated in the specification, is useful for treating diseases which respond to the blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.