Welcome to LookChem.com Sign In|Join Free

CAS

  • or

1201186-54-0

Post Buying Request

1201186-54-0 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

1201186-54-0 Usage

General Description

N-Tosyl-5-bromo-4,7-diazaindole is a chemical compound with the molecular formula C16H12BrN3O2S. It is a tosylated derivative of 5-bromo-4,7-diazaindole, which is a heterocyclic compound with potential pharmaceutical applications. The tosyl group in N-tosyl-5-bromo-4,7-diazaindole provides stability and protection to the molecule, making it useful in organic synthesis and medicinal chemistry. N-Tosyl-5-bromo-4,7-diazaindole has been studied for its potential as a building block in the synthesis of novel pharmaceutical compounds and as a precursor for the preparation of various biologically active molecules. Its unique chemical structure and reactivity make it a valuable tool in drug discovery and development research.

Check Digit Verification of cas no

The CAS Registry Mumber 1201186-54-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,1,1,8 and 6 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1201186-54:
(9*1)+(8*2)+(7*0)+(6*1)+(5*1)+(4*8)+(3*6)+(2*5)+(1*4)=100
100 % 10 = 0
So 1201186-54-0 is a valid CAS Registry Number.

1201186-54-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-bromo-5-(4-methylphenyl)sulfonylpyrrolo[2,3-b]pyrazine

1.2 Other means of identification

Product number -
Other names 2-bromo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1201186-54-0 SDS

1201186-54-0Relevant articles and documents

Preparation method of 2-bromo-5-p-toluenesulfonyl-5H-pyrrolo [2, 3-b] pyrazine

-

Paragraph 0029-0040, (2021/11/06)

The method comprises the following steps of: 1, dissolving 3-[(trimethylsilyl) ethynyl]-5-pyrazine-2-amine in a solvent N, N-dimethylacetamide, adding a mild alkali reagent, heating, and reacting for 0.5-2 hours; 2, cooling the reaction system to room temperature, adding paratoluensulfonyl chloride, cooling the reaction system to room temperature, and mkaing the reaction system react at room temperature for 0.5-2 hours; and 3, adding a product into a 0.5-10% wt sodium bicarbonate aqueous solution, and then filtering, recrystallizing, filtering and drying to obtain a finished product of the 2-bromo-5-p-toluenesulfonyl-5H-pyrrolo [2, 3-b] pyrazine. Compared with the prior art in which sodium hydride is adopted as an alkali reagent, the preparation method of the 2-bromo-5-p-toluenesulfonyl-5H-pyrrolo [2, 3-b] pyrazine provided by the invention has the following advantages that: the mild alkali reagent such as sodium tert-butoxide is used in the preparation process, and the purification mode is improved; reaction conditions are mild and controllable, and by-products in the reaction process are few; and the operation and post-treatment are simple, the product yield and quality are obviously improved, the production time and cost can be saved, and the method is suitable for industrial production.

IRAK4 kinase inhibitor and preparation method thereof

-

Paragraph 0115-0120; 0152-0157; 0187-0192; 0221-0226; 0252, (2021/02/05)

The present invention provides a compound represented by a general formula I, and a pharmaceutically acceptable salt, a stereoisomer, an ester, a prodrug, a solvate and a deuterated compound thereof,and the compound is an IRAK4 kinase inhibitor, and can be used for prevention and/or treatment of IRAK4 related diseases, such as autoimmune diseases, inflammatory diseases, cancers, heteroimmune diseases, thromboembolism, atherosclerosis, myocardial infarction and metabolic syndrome.

JAK kinase inhibitor, preparation method thereof, and application in the field of medicines

-

Paragraph 0268; 0271; 0274; 0275, (2019/04/10)

The application relates to a JAK kinase inhibitor, a preparation method thereof, and an application in the field of medicines and belongs to the field of medical chemistry. In the application, a series of novel small-molecular JAK inhibitors are provided and are represented as the general formula (II). The compounds have better effects and higher safety in prevention or treatment on JAK-related adaptation diseases.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1201186-54-0