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120143-22-8

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  • (3R,4R,5S)-4-azido-5-(((4-methylbenzoyl)oxy)methyl)tetrahydrofuran-2,3-diyl diacetate

    Cas No: 120143-22-8

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120143-22-8 Usage

Description

1,2-DI-O-ACETYL-3-AZIDO-3-DEOXY-5-O-TOLUOYL-D-RIBOFURANOSE is a complex organic chemical compound with a ribofuranose core structure. It is distinguished by the presence of two acetyl groups, an azido group, and a toluoyl group attached to the ribofuranose ring. 1,2-DI-O-ACETYL-3-AZIDO-3-DEOXY-5-O-TOLUOYL-D-RIBOFURANOSE is primarily utilized in organic synthesis and holds promise for applications in drug development and research of nucleoside analogs. Its intricate molecular structure makes it a valuable asset for studying the reactivity and properties of ribofuranose derivatives, potentially contributing to the design and development of innovative pharmaceutical compounds.

Uses

Used in Organic Synthesis:
1,2-DI-O-ACETYL-3-AZIDO-3-DEOXY-5-O-TOLUOYL-D-RIBOFURANOSE is used as a key intermediate in organic synthesis for the preparation of various complex organic molecules. Its unique functional groups facilitate multiple synthetic pathways, making it a versatile building block in the creation of novel chemical entities.
Used in Drug Development:
In the pharmaceutical industry, 1,2-DI-O-ACETYL-3-AZIDO-3-DEOXY-5-O-TOLUOYL-D-RIBOFURANOSE is used as a precursor in the synthesis of new drug candidates. Its structural features can be exploited to design molecules with specific biological activities, targeting a range of therapeutic areas.
Used in Nucleoside Analogs Research:
1,2-DI-O-ACETYL-3-AZIDO-3-DEOXY-5-O-TOLUOYL-D-RIBOFURANOSE is employed as a starting material in the research and development of nucleoside analogs. These analogs are crucial in the study of nucleic acid metabolism, antiviral and anticancer drug discovery, and the understanding of fundamental biological processes.
Used in Academic Research:
In academic settings, 1,2-DI-O-ACETYL-3-AZIDO-3-DEOXY-5-O-TOLUOYL-D-RIBOFURANOSE serves as a model compound for studying the reactivity and properties of ribofuranose derivatives. Its complex structure provides insights into the design of new chemical reactions and the exploration of novel synthetic methodologies.

Check Digit Verification of cas no

The CAS Registry Mumber 120143-22-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,0,1,4 and 3 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 120143-22:
(8*1)+(7*2)+(6*0)+(5*1)+(4*4)+(3*3)+(2*2)+(1*2)=58
58 % 10 = 8
So 120143-22-8 is a valid CAS Registry Number.

120143-22-8 Well-known Company Product Price

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  • Aldrich

  • (712825)  1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(p-toluoyl)-D-ribofuranose  ≥95% (HPLC)

  • 120143-22-8

  • 712825-100MG

  • 5,100.03CNY

  • Detail

120143-22-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,2-DI-O-ACETYL-3-AZIDO-3-DEOXY-5-O-TOLUOYL-D-RIBOFURANOSE

1.2 Other means of identification

Product number -
Other names 3-azido-1,2-bis-O-acetyl-5-O-toluoyl-3-deoxy-D-ribofuranose

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:120143-22-8 SDS

120143-22-8Upstream product

120143-22-8Relevant articles and documents

Synthesis of 3'-amino-3'-deoxyadenosine derivatives as potential drugs for the treatment of malaria

Soenens,Francois,Van den Eeckhout,Herdewijn

, p. 409 - 411 (1995)

A series of 3'-substituted 3'-amino-3'-deoxyadenosine analogues were synthesized and subsequently tested against the human malaria parasite Plasmodium falciparum in vitro. Several amongst them displayed pronounced antiplasmodial activities.

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