120158-74-9Relevant academic research and scientific papers
ISOMERIZATION OF 5-ACYL-6-HALO-1,6-DIAZABICYCLOHEXANES, A CASE OF INVERSION RATHER THAN 1,2-ACYL MIGRATION
Shustov, G. V.,Denisenko, S. N.,Chervin, I. I.,Zolotoi, A. B.,D'yachenko, O. A.,et all
, p. 1076 - 1079 (2007/10/02)
X-ray diffraction structural analysis and 13 C and 15 N NMR spectroscopy were used to establish that the final product of the halogenation of 5-acyl-1,6-diazabicyclohexane is the oxo-6-halo derivative.Thus, the observed transformation of the initially formed endo-N-chloro isomer is an inversion and not 1,2-acyl migration as previously proposed.
