1201591-69-6Relevant articles and documents
Cell-based optimization of novel benzamides as potential antimalarial leads
Wu, Tao,Nagle, Advait,Sakata, Tomoyo,Henson, Kerstin,Borboa, Rachel,Chen, Zhong,Kuhen, Kelli,Plouffe, David,Winzeler, Elizabeth,Adrian, Francisco,Tuntland, Tove,Chang, Jonathan,Simerson, Susan,Howard, Steven,Ek, Jared,Isbell, John,Deng, Xianming,Gray, Nathanael S.,Tully, David C.,Chatterjee, Arnab K.
scheme or table, p. 6970 - 6974 (2010/07/03)
Screening our in-house compound collection using a cell based Plasmodium falciparum proliferation assay we discovered a known pan-kinase inhibitor scaffold as a hit. Further optimization of this series led us to a novel benzamide scaffold which was devoid