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4-Chloro-5-(trifluoromethyl)pyrimidin-2-amine is a pyrimidine derivative with the molecular formula C5H3ClF3N3. It features a chloro substituent at the 4 position and a trifluoromethyl substituent at the 5 position. This chemical compound has garnered interest due to its biological activities and potential applications in pharmaceuticals and agrochemicals.

1201657-24-0

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1201657-24-0 Usage

Uses

Used in Pharmaceutical Industry:
4-Chloro-5-(trifluoromethyl)pyrimidin-2-amine is used as an intermediate in the synthesis of various pharmaceutical products. Its anti-inflammatory and antiproliferative properties make it a promising candidate for the development of new drugs targeting inflammation and cell proliferation disorders.
Used in Agrochemical Industry:
In the agrochemical field, 4-Chloro-5-(trifluoromethyl)pyrimidin-2-amine serves as an intermediate for the production of agrochemicals. Its biological activities can be harnessed to develop new pesticides or herbicides that can effectively control pests and weeds, contributing to increased crop yields and agricultural productivity.
Used in Organic Synthesis:
4-Chloro-5-(trifluoromethyl)pyrimidin-2-amine is also used as a building block in organic synthesis. Its unique structure and functional groups make it a valuable component in the creation of complex organic molecules for various applications, including the development of new materials, dyes, and other specialty chemicals.

Check Digit Verification of cas no

The CAS Registry Mumber 1201657-24-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,1,6,5 and 7 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1201657-24:
(9*1)+(8*2)+(7*0)+(6*1)+(5*6)+(4*5)+(3*7)+(2*2)+(1*4)=110
110 % 10 = 0
So 1201657-24-0 is a valid CAS Registry Number.

1201657-24-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-chloro-5-(trifluoromethyl)pyrimidin-2-amine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1201657-24-0 SDS

1201657-24-0Downstream Products

1201657-24-0Relevant academic research and scientific papers

SUBSTITUTED PYRIMIDINES AND TRIAZINES AS HERBICIDES

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Page/Page column 58, (2021/09/17)

Disclosed are compounds of Formula I, stereoisomers, TV-oxides, and salts thereof, wherein; A is selected from A-2, A-2, A-3, A-4, A-5, A-6, A-7, A-8, A-9 and A-10 and A, A-l, A-2, A-3, A-4, A-5, A-6, A-7, A-8, A-9, A-10, R1 through R20b, W, X and Y are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula I and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound or a composition of the invention.

DIAMINO-SUBSTITUTED PYRIDINES AND PYRIMIDINES AS HERBICIDES

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Page/Page column 41; 42, (2020/08/22)

Disclosed are compounds of Formula 1, including all stereoisomers, A-oxides, and salts thereof, wherein A is selected from and X, Q1, Q2, Q3, Q4, R, R1, R2, R3, R4 and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound or a composition of the invention.

Oxadiazolopyridine Derivates for Use as Ghrelin O-Acyl Transferase (GOAT) Inhibitors

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Paragraph 0471-0474, (2018/03/01)

The present invention relates to compounds of general formula I, wherein the groups R1, R2 and n are defined as in claim 1, which have valuable pharmacological properties, in particular bind to ghrelin O-acyl transferase (GOAT) and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular obesity.

PYRIMIDINE OR PYRIDINE DERIVATIVES USEFUL AS PI3K INHIBITORS

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Paragraph 00610; 00611, (2015/11/23)

Compounds (I) and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including P13 kinase activity, are described herein.

HETEROCYCLIC COMPOUNDS AND USES THEREOF

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Page/Page column 118, (2012/05/21)

Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein.

CHEMICAL COMPOUNDS, COMPOSITIONS AND METHODS FOR KINASE MODULATION

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Page/Page column 112, (2011/12/04)

Chemical compounds that modulate kinase activity, including PI3 kinase activity, and chemical compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein.

PYRIMIDINE DERIVATIVES AND THEIR USE FOR CONTROLLING UNDESIRED PLANT GROWTH

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Page/Page column 25, (2010/07/08)

Compounds of the formula (I) and their agrochemically compatible salts and their use in the field of crop protection are described.

Pyrimidine derivatives and their use for controlling undesired plant growth

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Page/Page column 24-25, (2010/07/08)

Pyrimidine derivatives and their use for controlling undesired plant growth Compounds of the formula (I) and their use in the field of crop protection are described.

IMIDAZOPYRIDINE DERIVATIVES AS INHIBITORS OF RECEPTOR TYROSINE KINASES

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Page/Page column 128, (2010/01/07)

The invention relates to new bicyclic heterocyclic derivative compounds, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

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