120173-41-3Relevant articles and documents
Reversible Multistimuli Switching of a Spiropyran-Functionalized Organic Cage in Solid and Solution
Mondal, Bijnaneswar,Ghosh, Aloke Kumar,Mukherjee, Partha Sarathi
, p. 7783 - 7790 (2017)
A spiropyran-decorated covalent organic cage (PC2) has been designed, employing dynamic imine chemistry followed by imine bond reduction. The molecule is capable of altering its color upon exposure to external stimuli such as heat and light. Construction of a 3D organic cage introduces a new piece to the system by swapping the closed form with the open form in the solid state with diverse color change. Moreover, this material has high chemical stability and is capable of reversible stimuli-responsive color change without any degradation for an extended period.
AMINOGUANIDINE HYDRAZONES AS RETROMER STABILIZERS USEFUL FOR TREATING NEUROLOGICAL DISEASES
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Page/Page column 21; 46; 50-51, (2020/10/20)
The present invention relates to novel aminoguanidine hydrazone-derivatives of Formula (I) which are effective as retromer stabilizers and useful as neuroprotecting drugs. The invention also relates to pharmaceutical compositions comprising the compounds and their use in therapy and diagnostic.
Hexagon wreaths: Self-assembly of discrete supramolecular fractal architectures using multitopic terpyridine ligands
Wang, Ming,Li, Xiaopeng,Wang, Chao,Hao, Xin-Qi,Liu, Jingjing,Li, Xiaohong,Xu, Chenglong,Lopez, Alberto,Sun, Luyi,Song, Mao-Ping,Yang, Hai-Bo
, p. 6664 - 6671 (2014/05/20)
In this study, we overcame a challenge in conventional self-assembly of macrocycles that uses ditopic 2,2:6,2-terpyridine (tpy) building blocks with a 120angle between two ligating moieties, which generally produces a mixture of multiple macrocycles instead of a single hexagon. Two supramolecular hexagon wreaths, [Zn9LA6] and [Zn12LB6], were designed and self-assembled from tritopic and tetratopic tpy ligands with Zn(II) ions, respectively. These multitopic ligands, bearing multiple binding sites, increased the total density of coordination sites and provided high geometric constraints to induce the formation of discrete structures. Such hexagon wreaths, which were constructed by simple recursion of small hexagons around a central hexagon, exhibit fractal geometry features with self-similarity at different levels. The shapes, sizes, and structures were fully characterized by NMR, ESI-MS, traveling-wave ion mobility mass spectrometry (TWIM-MS), and transmission electron microscopy. With diameters around 5.5 nm for [Zn 9LA6] and 5.8 nm for [Zn12LB6], the remarkable rigidity of these fractal architectures was supported by TWIM-MS, in contrast to the high flexibility of macrocycles assembled by ditopic tpy ligands.