1201808-24-3

Usage

Uses

Used in Cancer Prevention:
2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-(phenylMethoxy)-4H-1-benzopyran-4-one is used as a cancer prevention agent due to its strong antioxidant and radical scavenging properties. It is suggested to play a role in preventing the formation and progression of cancer by neutralizing reactive oxygen species and protecting cells from oxidative damage.
Used in Pharmaceutical Industry:
2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-(phenylMethoxy)-4H-1-benzopyran-4-one is used as a pharmaceutical candidate for the development of new drugs and therapies. Its strong antioxidant and radical scavenging properties make it a promising candidate for the treatment of various diseases and conditions, including cancer, neurodegenerative disorders, and inflammatory diseases.
Used in Cosmetic Industry:
2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-(phenylMethoxy)-4H-1-benzopyran-4-one is used as an active ingredient in cosmetic products for its antioxidant and anti-aging properties. It can help protect the skin from oxidative damage, reduce the appearance of fine lines and wrinkles, and promote a more youthful and radiant complexion.
Used in Food Industry:
2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-(phenylMethoxy)-4H-1-benzopyran-4-one is used as a natural antioxidant in the food industry to extend the shelf life of food products and protect them from oxidation and spoilage. Its strong antioxidant properties can help preserve the nutritional value and quality of food products, while also providing potential health benefits to consumers.
Used in Nutraceutical Industry:
2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-(phenylMethoxy)-4H-1-benzopyran-4-one is used as a nutraceutical ingredient for its health-promoting properties. It can be incorporated into dietary supplements and functional foods to provide consumers with the benefits of its antioxidant and anti-inflammatory properties, as well as its potential role in cancer prevention and other health-related applications.

Upstream product

• 1201808-23-2 5,7-bis(benzyloxy)-2-(2,2-diphenylbenzo[d][1,3]dioxol-5-yl)-4H-chromen-4-one 

Downstream Products

• 1201808-25-4 7-benzyloxy-2-(4-ethoxy-3-hydroxyphenyl)-5-hydroxy-4H-chromen-4-one 
• 1201808-30-1 7-benzyloxy-2-(3,4-diethoxyphenyl)-5-hydroxy-4H-chromen-4-one 
• 1201808-26-5 7-benzyloxy-2-(3-hydroxy-4-(isopentyloxy)phenyl)-5-hydroxy-4H-chromen-4-one 

Relevant academic research and scientific papers

Discovery and synthesis of novel luteolin derivatives as DAT agonists

Luteolin, 5,7-dihydroxy-2-(3,4-dihydroxyphenyl)-4H-chromen-4-one, has been proposed and proved to be a novel dopamine transporter (DAT) activator. In order to develop this potential of luteolin, a series of novel luteolin derivatives were designed, synthesized, and evaluated for their DAT agonistic activities, utilizing constructed Chinese hamster ovary (CHO) cell lines stably expressing rat DAT. Biological screening results demonstrated that luteolin derivatives 1d, 1e, and 4c carry great DAT agonistic potency (EC50 = 0.046, 0.869, and 1.375 μM, respectively) compared with luteolin 8 (EC50 = 1.45 ± 0.29 μM). Luteolin derivative 1d, notably, exhibited a 32-fold-higher DAT agonistic potency than luteolin. These luteolin derivatives represent a novel DAT agonist class, from which lead compounds useful for exploration of additional novel DAT agonists could be drawn.