1201898-60-3Relevant academic research and scientific papers
First asymmetric total synthesis of aspinolide A
Chowdhury, Partha Sarathi,Gupta, Priti,Kumar, Pradeep
, p. 7018 - 7020 (2009)
The first total synthesis of aspinolide A has been achieved using ring-closing metathesis as a key step. The stereogenic centers were generated by means of hydrolytic kinetic resolution (HKR) of racemic epoxides.
Stereoselective formal synthesis of aspergillide A
Sabitha, Gowravaram,Vasudeva Reddy,Senkara Rao,Yadav
scheme or table, p. 4195 - 4198 (2010/09/12)
The stereoselective formal synthesis of aspergillide A (1), a cytotoxic 14-membered macrolide, is disclosed. The key intermediate, a trisubstituted tetrahydropyran core is prepared by SmI2-induced intramolecular reductive cyclization as well as
