1201905-61-4

Basic information

• Product Name: (E)-1-Ethoxyethene-2-ylboronic acid pinacol ester
• Synonyms: (E)-1-Ethoxyethene-2-ylboronic acid pinacol ester;(E)-1-Ethoxyethene-2-boronic acid pinacol ester;1,3,2-Dioxaborolane, 2-[(1E)-2-ethoxyethenyl]- 4,4,5,5-tetraMethyl-;trans-2-Ethoxyvinylboronic acid pinacol ester 97%;(E)-2-(2-Ethoxyvinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;(E)-2-Ethoxyvinylboronic acid pinacol ester;trans-2-Ethoxyvinylboronic acid pinacol ester;(E)-3-hydroxy-2,3-dimethylbutan-2-yl hydrogen 2-ethoxyvinylboronate
• CAS NO: 1201905-61-4
• Molecular Formula: C₁₀H₁₉BO₃
• Molecular Weight: 216.08234
• Mol File: 1201905-61-4.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 50℃/0.3mm
• Flash Point: 86℃
• Appearance: /
• Density: 0.935 g/mL at 25 °C
• Refractive Index: 1.4460
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (E)-1-Ethoxyethene-2-ylboronic acid pinacol ester(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-Ethoxyethene-2-ylboronic acid pinacol ester(1201905-61-4)
• EPA Substance Registry System: (E)-1-Ethoxyethene-2-ylboronic acid pinacol ester(1201905-61-4)

Safety Data

• RIDADR: NA 1993 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 1201905-61-4(Hazardous Substances Data)

Usage

Uses

trans-2-Ethoxyvinylboronic acid pinacol ester is a boronic ester commonly used in Suzuki-Miyaura cross-coupling.This reaction is a key step to synthesize:Azaindole and diazaindoles from chloroamino-N-heterocycles.Doryanine and its derivatives from 2-bromobenzoic acid.

Upstream product

• 109-92-2 ethyl vinyl ether 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 
• 927-80-0 1-ethoxyacetylene 

Downstream Products

• 1578246-51-1 (E)-methyl 2-(benzyloxy)-5-(2-ethoxyvinyl)isonicotinate 

Relevant articles and documents

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This study describes a very efficient strategy for the synthesis of two new bridged-nicotine analogues. Starting from either 4- or 3-chloropyridine the desired tricyclic ring systems are accessed in just three steps in 23% and 40% overall yield, respectively.

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