1201935-85-4Relevant academic research and scientific papers
C-H Amination of Nitro Azaheterocyclic Compounds by Vicarious Nucleophilic Substitution
Zhou, Ru-Shuang,Cai, Chun
supporting information, p. 88 - 92 (2021/12/03)
Various nitro azaheterocyclic compounds were subjected to C H amination by vicarious nucleophilic substitution with 4H-1,2,4-triazol-4-amine (ATA). The aminated products were characterized by NMR, mass spectroscopy, and single-crystal X-ray diffraction an
AROMATIC HETEROCYCLIC COMPOUND WITH KINASE INHIBITORY ACTIVITY
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Paragraph 0098-0100, (2021/07/29)
Provided are a JAK kinase inhibitor, preparation and use thereof. In particular, provided is a compound of Formula I, wherein each group is as described in the specification. The compound has an excellent JAK inhibitory activity, and therefore can be used to prepare pharmaceutical compositions for the treatment of cancer and other diseases related to JAK activity.
Alkynyl pyrimidine or alkynyl pyridine compound as well as composition and application thereof
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Paragraph 0097; 0098; 0101, (2020/08/18)
The invention relates to alkynyl pyrimidine or alkynyl pyridine compounds represented by a formula (I) or pharmaceutically acceptable salts, isomers, solvates, crystals or prodrugs thereof. The invention also discloses a pharmaceutical composition contain
PYRIDINE COMPOUNDS
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Page/Page column 208, (2010/01/12)
The present invention relates to compounds that inhibit of focal adhesion kinase function, processes for their preparation, pharmaceutical compositions containing them as the active ingredient, to their use as medicaments and to their use in the manufacture of medicaments for use in the treatment in warm-blooded animals such as humans of diseases such as cancer.
