1201947-04-7

Basic information

• Product Name: N₁,N₁-dibenzyl-N₃-(2-(7-chloroquinolin-4-ylamino)ethyl)propane-1,3-diamine
• CAS NO: 1201947-04-7
• Molecular Weight: 459.034
• Mol File: 1201947-04-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N₁,N₁-dibenzyl-N₃-(2-(7-chloroquinolin-4-ylamino)ethyl)propane-1,3-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: N₁,N₁-dibenzyl-N₃-(2-(7-chloroquinolin-4-ylamino)ethyl)propane-1,3-diamine(1201947-04-7)
• EPA Substance Registry System: N₁,N₁-dibenzyl-N₃-(2-(7-chloroquinolin-4-ylamino)ethyl)propane-1,3-diamine(1201947-04-7)

Safety Data

• Hazardous Substances Data: 1201947-04-7(Hazardous Substances Data)

Upstream product

• 5407-57-8 N-(7-chloroquinolin-4-yl)ethylenediamine 
• 16045-94-6 3-(dibenzylamino)-n-propyl chloride 

Relevant articles and documents

Reversal agent and linker variants of reversed chloroquines: Activities against Plasmodium falciparum

We have shown that "reversed chloroquine molecules" constructed from chloroquine-like and resistance "reversal-agent"-like cores can be powerful drugs against malaria (J. Med. Chem. 2006, 49, 5623-5625). Several reversed chloroquines are now presented that probe parameters governing the activities against chloroquine-resistant and chloroquine-sensitive malaria strains. The design is tolerant to linker and reversal agent changes, but a piperazinyl group adjacent to the quinoline, at least for the group of compounds studied here, may be detrimental. 2009 American Chemical Society.