1202044-20-9

Basic information

• Product Name: Ostarine(MK-2866)
• Synonyms: (2S)-3-(4-Cyanophenoxy-2,3,5,6-d4)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide;((2s)-3-(4-cyanophenoxy)-N-[4-cyano-3-(trifluoroMethyl)phenyl]-2-hydroxy-2-MethylpropanaMide);Ostarine (MK-2866, GTx-024);Ostarine(MK-2866);MK-2866 Ostarine;(2S)-3-(4-cyano-2,3,5,6-tetradeuteriophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide;MK-2866 MK-2866 White powder 99%;Factory Supply best quality Ostarine(MK-2866) 1202044-20-9 CAS NO.1202044-20-9
• CAS NO: 1202044-20-9
• Molecular Formula: C₁₉H₁₄F₃N₃O₃
• Molecular Weight: 389.33
• Mol File: 1202044-20-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 632.261 °C at 760 mmHg
• Flash Point: 336.18 °C
• Appearance: /
• Density: 1.418 g/cm³
• CAS DataBase Reference: Ostarine(MK-2866)(CAS DataBase Reference)
• NIST Chemistry Reference: Ostarine(MK-2866)(1202044-20-9)
• EPA Substance Registry System: Ostarine(MK-2866)(1202044-20-9)

Safety Data

• Hazardous Substances Data: 1202044-20-9(Hazardous Substances Data)

Usage

Description

Ostarine (MK-2866) is an investigational selective androgen receptor modulator (SARM) that has not yet been approved by the US Food and Drug Administration (FDA). It is a synthetic compound designed to selectively target androgen receptors, with the aim of promoting muscle growth and bone density without the side effects associated with traditional anabolic steroids.

Uses

Used in Pharmaceutical Industry:
Ostarine (MK-2866) is used as a therapeutic agent for the treatment of conditions such as muscle wasting and osteoporosis. It works by selectively binding to androgen receptors, stimulating muscle growth and improving bone density, while minimizing the risk of side effects commonly associated with anabolic steroids.
Used in Research and Development:
Ostarine (MK-2866) is also used in research and development for the study of its potential benefits and side effects. As an investigational drug, it is being evaluated for its efficacy and safety in clinical trials, with the goal of understanding its full potential as a treatment for various conditions related to muscle wasting and bone health.

Mechanism

Ostarine(MK-2866) attaches to proteins in the body known as androgen receptors. When ostarine binds to these receptors, it tells the muscles in the body to grow. Unlike some other chemicals that bind to androgen receptors, such as?steroids, ostarine doesn't seem to cause as many side effects in other parts of the body.

Health effects

The FDA have warned that SARMs can have serious side effects ranging from risk of heart attack to stroke and liver damage.

InChI:InChI=1/C19H14F3N3O3/c1-18(27,11-28-15-6-2-12(9-23)3-7-15)17(26)25-14-5-4-13(10-24)16(8-14)19(20,21)22/h2-8,27H,11H2,1H3,(H,25,26)/t18-/m1/s1

Synthetic route

4-cyanophenol-d4 (1025089-21-7) + (2R)-3-bromo-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide (206193-17-1) → (S)-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide-d4 (1202044-20-9)

Conditions	Yield
With sodium carbonate In acetone for 3h; Reflux;	59.9%

Upstream product

• 1025089-21-7 4-cyanophenol-d4 
• 206193-17-1 (2R)-3-bromo-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide 

Relevant articles and documents

METABOLITES OF SELECTIVE ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF

This invention provides metabolites of SARM compounds including inter alia glucuronidated metabolites and uses thereof in treating a variety of diseases or conditions in a subject, including, inter alia, muscle wasting disease and/or disorder, a bone related disease and/or disorder, metabolic syndrome, diabetes and associated diseases, and others.