1202075-85-1Relevant articles and documents
Synthesis and evaluation of pyrrolin-2-one compounds, a series of plasminogen activator inhibitor-1 inhibitors
Miyazaki, Hiroshi,Ogiku, Tsuyoshi,Sai, Hiroshi,Moritani, Yasunori,Ohtani, Akio,Ohmizu, Hiroshi
experimental part, p. 979 - 985 (2010/03/23)
A novel series of furan-2-one and pyrrolin-2-one derivatives having PAI-1 (plasminogen activator inhibitor-1) inhibitory activity were synthesized and evaluated for their antithrombotic activity in a rat arterial thrombosis model. Among the synthesized co