120208-23-3

Upstream product

• 90-05-1 2-methoxy-phenol 

Downstream Products

• 125629-42-7 1,5-diiodo-2,3-dimethoxybenzene 
• 1402061-46-4 C₂₇H₂₆N₂O₄S₂ 
• 1375479-00-7 C₁₂H₁₄I₂OSi 
• 1375478-99-1 C₈H₅F₃I₂O₄S 
• 125629-44-9 1,2-dimethoxy-3,5-bis<(trifluoromethyl)sulfonyl>benzene 
• 125629-20-1 3,5-bis<(trifluoromethyl)sulfonyl>benzene-1,2-diol 
• 125629-43-8 1,2-dimethoxy-3,5-bis<(trifluoromethyl)thio>benzene 
• 646054-35-5 (2,4-diiodo-6-methoxycarbonylmethoxy-phenoxy)acetic acid methyl ester 
• 646054-34-4 (2,4-diiodo-6-methoxy-phenoxy)acetic acid methyl ester 

Relevant academic research and scientific papers

The First Direct Chlorination of Iodoarenes - A Side-chain Directed Process

The chlorination of electron rich iodoarenes with MoCl5 proceeds with methoxycarbonylmethyl as the directing group. The transformation is selective and without loss of the valuable iodo substituent.

Catalytic generation of arynes and trapping by nucleophilic addition and iodination

A fair exchange: In the title reaction, alkynyllithium serves as an initiator for benzyne generation through an iodine-lithium exchange (see scheme; Tf=trifluoromethanesulfonyl). When performed in the presence of stoichiometric amounts of a nucleophile, the generated benzyne undergoes attack by lithio nucleophiles to generate aryllithium, which is then iodinated by iodoalkyne to give the iodoarenes 1. Copyright

Iodinated biaryls synthesized by the direct dehydrodimerization of iodoarenes using phenyliodine(III) bis(trifluoroacetate) (PIFA)

Multiply iodinated biaryls can be prepared in yields up to 75% by direct oxidative coupling reaction of the iodinated arenes. The PIFA-mediated dehydrodimerization is superior to all other known methods. The developed protocol is reliable and easy to perform.