1202160-15-3Relevant academic research and scientific papers
Selective unusual pd-mediated biaryl coupling reactions: Solvent effects with carbonate bases
Donati, Ludovic,Michel, Sylvie,Tillequin, Francois,Poree, Francois-Hugues
supporting information; experimental part, p. 156 - 158 (2010/03/25)
"Chemical Equation Presented" A one-step Pd-catalyzed reaction performed on an o-bromobenzamide permitted the selective formation of either phenanthridinones 2 via an ipso substitution or new phenanthridinone-1- carboxamides 3 through a direct N-arylation. A direct correlation between the solvent polarity and the carbonate base on the selectivity has been observed. The proposed catalytic cycle involves the initial formation of a common intermediate and depends on the base assistance.
