1202168-38-4Relevant articles and documents
Combretastatin-like chalcones as inhibitors of microtubule polymerisation. Part 2: Structure-based discovery of alpha-aryl chalcones
Ducki, Sylvie,Mackenzie, Grant,Greedy, Ben,Armitage, Simon,Chabert, Jeremie Fournier Dit,Bennett, Elizabeth,Nettles, Jim,Snyder, James P.,Lawrence, Nicholas J.
, p. 7711 - 7722 (2009)
Tubulin is an important molecular target in cancer chemotherapy. Antimitotic agents able to bind to the protein are currently under study, commonly used in the clinic to treat a variety of cancers and/or exploited as probes to investigate the protein's st