1202184-16-4Relevant articles and documents
Design, synthesis, and biological activity of bicyclic radester analogues as Hsp90 inhibitors
Jadhav, Vinod D.,Duerfeldt, Adam S.,Blagg, Brian S.J.
, p. 6845 - 6850 (2009)
Bicyclic radester analogues have been synthesized and evaluated for Hsp90 inhibitory activity. These analogues induce concentration-dependent degradation of Hsp90-dependent client proteins with the six-membered bicyclic analogues manifesting increased act