1202184-22-2Relevant articles and documents
Design, synthesis, and biological activity of bicyclic radester analogues as Hsp90 inhibitors
Jadhav, Vinod D.,Duerfeldt, Adam S.,Blagg, Brian S.J.
scheme or table, p. 6845 - 6850 (2010/05/19)
Bicyclic radester analogues have been synthesized and evaluated for Hsp90 inhibitory activity. These analogues induce concentration-dependent degradation of Hsp90-dependent client proteins with the six-membered bicyclic analogues manifesting increased act