1202194-31-7

Basic information

• Product Name: C₂₂H₃₁N₃O₃S
• Synonyms: C₂₂H₃₁N₃O₃S
• CAS NO: 1202194-31-7
• Molecular Weight: 417.572
• Mol File: 1202194-31-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₃₁N₃O₃S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₃₁N₃O₃S(1202194-31-7)
• EPA Substance Registry System: C₂₂H₃₁N₃O₃S(1202194-31-7)

Safety Data

• Hazardous Substances Data: 1202194-31-7(Hazardous Substances Data)

Upstream product

• 1202405-40-0 (R)-2-cyano-N-(1-phenylethyl)acetamide 
• 124754-81-0 tert-butyl [(1R)-2-methyl-1-(2-oxoethyl)propyl]carbamate 

Relevant articles and documents

Cyanoacetamide MCR (III): Three-component Gewald reactions revisited

Cyanoacetic acid derivatives are the starting materials for a plethora of multicomponent reaction (MCR) scaffolds. Here we describe valuable general protocols for the synthesis of arrays of 2-aminothiophene-3carboxamides from cyanoacetamides, aldehydes or ketones, and sulfur via a Gewald-3CR variation, In many cases the reactions involve a very convenient work up by simple precipitation in water and filtration. More than 40 new products are described, We foresee our protocol and the resulting derivatives to become very valuable to greatly expanding the MCR scaffold space of cyanoacetamide derivatives.