1202207-13-3

Upstream product

• 1202207-11-1 ethyl 1-(3,5-dichloro-4-(4-methoxybenzyloxy)phenyl)-1H-1,2,4-triazole-3-carboxylate 

Downstream Products

• 1202207-14-4 1-(3,5-Dichloro-4(4-methoxybenzyloxy)phenyl)-N-(3,3-dimethylbutyl)-1H-1,2,4-triazole-3-carboxamide 
• 1219013-53-2 1-(3,5-dichloro-4-(4-methoxybenzyloxy)phenyl)-N-(4-hydroxybenzyl)-1H-1,2,4-triazole-3-carboxamide 
• 1219013-54-3 1-(3,5-dichloro-4-(4-methoxybenzyloxy)phenyl)-N-(3,3-dimethyl-2-oxobutyl)-1H-1,2,4-triazole-3-carboxamide 
• 1228632-33-4 1-(3,5-dichloro-4-(4-methoxybenzyloxy)phenyl)-N-hydroxy-N-(4-phenoxybenzyl)-1H-1,2,4-triazole-3-carboxamide 

Relevant academic research and scientific papers

COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING IMIDAZOLE AND TRIAZOLE DERIVATIVES

The present invention relates to compositions and methods for treating a disease in an animal, which disease is responsive to inhibiting of functional cystic fibrosis transmembrane conductance regulator (CFTR) polypeptide by administering to a mammal in need thereof an effective amount of a compound defined herein (including those compounds set forth in Tables 1-3 or encompassed by formulas (I), (IA), (IB), (II), and (III)) or compositions thereof, thereby treating the disease. The present invention particularly, relates to a method of treating diarrhea and polycystic kidney disease.