1202223-58-2Relevant articles and documents
Synthesis of 2-thio- and 2-oxoimidazoles via cascade addition- cycloisomerization reactions of propargylcyanamides
Giles, Robert L.,Nkansah, Richard A.,Looper, Ryan E.
supporting information; experimental part, p. 261 - 264 (2010/04/06)
(Chemical Equation Presented) A methodology to generate 2-thio- and 2-oxoimidazoles through an addition-cyclization-isomerization reaction of propargylcyanamides with thiol and alcohol nucleophiles is described. In general, the reaction sequence allows for the rapid formation of highly substituted 2-thio- and 2-oxoimidazoles in good to excellent yields.