120230-72-0

Upstream product

• 120230-62-8 dimethyl (S)-N-(9-phenyl-9H-fluoren-9-yl)aspartate 
• 120230-69-5 (2S,3R)-methyl 4-hydroxy-3-methyl-2-(9-phenyl-9H-fluoren-9-ylamino)butanoate 
• 851120-78-0 dimethyl N-(9-phenylfluorenyl)-3-methyl-L-aspartate 
• 120230-68-4 methyl (2S)-2-<(9-phenylfluorenyl)amino>-3-methyl-4-hydroxybutanoate 

Downstream Products

• 851120-79-1 (2S,3S)-methyl 4-(1-isopropylpiperidin-4-ylamino)-3-methyl-2-(9-phenyl-9H-fluoren-9-ylamino)butanoate 
• 120328-53-2 (S)-2-[(3S,4S)-4-Methyl-2-oxo-3-(9-phenyl-9H-fluoren-9-ylamino)-pyrrolidin-1-yl]-propionic acid methyl ester 
• 120328-55-4 (R)-2-[(3S,4S)-4-Methyl-2-oxo-3-(9-phenyl-9H-fluoren-9-ylamino)-pyrrolidin-1-yl]-propionic acid methyl ester 
• 120328-52-1 (2S,3S)-4-((R)-1-Methoxycarbonyl-ethylamino)-3-methyl-2-(9-phenyl-9H-fluoren-9-ylamino)-butyric acid methyl ester 
• 120328-50-9 (2S,3S)-4-((S)-1-Methoxycarbonyl-ethylamino)-3-methyl-2-(9-phenyl-9H-fluoren-9-ylamino)-butyric acid methyl ester 

Relevant academic research and scientific papers

Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors

The present application describes sulfonylaminovalerolactams and derivatives thereof of Formula Ia-If: or pharmaceutically acceptable salt forms thereof, wherein ring G is a mono- or bicyclic carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.

Conformationally Constrained Peptides. Chirospecific Synthesis of 4-Alkyl-Substituted γ-Lactam-Bridged Dipeptides from L-Aspartic Acid

The synthesis of enantiomerically pure γ-lactam-bridged dipeptide analogues of Val-Ala, Ile-Ala, and β-MeLeu-Ala starting from L-aspartic acid is presented.N-(9-Phenylfluorenyl)-L-aspartic acid α-tert-butyl β-methyl diester and N-(9-Phenylfluorenyl)-L-asp