1202402-07-0Relevant academic research and scientific papers
Highly efficient access to iminoisocoumarins and α-iminopyrones via AgOTf-catalyzed intramolecular enyne-amide cyclization
Bian, Ming,Yao, Weijun,Ding, Hanfeng,Ma, Cheng
supporting information; experimental part, p. 269 - 272 (2010/04/06)
(Chemical Equation Presented) Iminoisocoumarins and α-iminopyrones are prepared via Sonogashira coupling and AgOTf-catalyzed 6-endo-dig O-cyclization of the enyne-amide system in dichloroethane, in one pot or stepwise, respectively.
Silver-catalyzed intramolecular cyclization of o-(1-Alkynyl)benzamides: Efficient synthesis of (1H)-isochromen-1-imines
Liu, Guannan,Zhou, Yu,Ye, Deju,Zhang, Dengyou,Ding, Xiao,Jiang, Hualiang,Liu, Hong
supporting information; experimental part, p. 2605 - 2610 (2009/12/29)
An efficient avenue for the facile and atom-economic synthesis of (1H)-isochromen-1imines has been developed, and a broad spectrum of substrates can participate in the process effectively to produce the desired products in good yields. Significantly, this is the first report of the synthesis of (1H)-isochromen-l-imines that involves a silver(I)-catalyzed, regiocontrolled intramolecular addition of the carbonyl group of the amide moiety towards an alkyne.
