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3-{4-[(3,4-dichlorobenzyl)oxy]phenyl}-3-ethoxy propanoic acid is a complex organic compound with the molecular formula C19H18Cl2O5. It is a derivative of propanoic acid, featuring a 3-ethoxy group and a 4-[(3,4-dichlorobenzyl)oxy]phenyl substituent. This chemical is characterized by the presence of two chlorine atoms attached to the benzyl group, which is connected to the phenyl ring through an ether linkage. The compound has potential applications in pharmaceuticals and chemical research due to its unique structure and functional groups.

1202575-18-5

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1202575-18-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1202575-18-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,2,5,7 and 5 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1202575-18:
(9*1)+(8*2)+(7*0)+(6*2)+(5*5)+(4*7)+(3*5)+(2*1)+(1*8)=115
115 % 10 = 5
So 1202575-18-5 is a valid CAS Registry Number.

1202575-18-5Relevant academic research and scientific papers

Optimization of 3-aryl-3-ethoxypropanoic acids and discovery of the potent GPR40 agonist DS-1558

Takano, Rieko,Yoshida, Masao,Inoue, Masahiro,Honda, Takeshi,Nakashima, Ryutaro,Matsumoto, Koji,Yano, Tatsuya,Ogata, Tsuneaki,Watanabe, Nobuaki,Hirouchi, Masakazu,Kimura, Takako,Toda, Narihiro

, p. 5546 - 5565 (2015/11/11)

GPR40 agonists stimulate insulin secretion only under the presence of high glucose concentration. Based on this mechanism, GPR40 agonists are believed to be promising novel insulin secretagogues with low risk of hypoglycemia. The optimizations of 3-aryl-3-ethoxypropanoic acids were performed to improve in vitro activity. We discovered compound 29r (DS-1558), (3S)-3-ethoxy-3-(4-{[(1R)-4-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl]oxy}phenyl)propanoic acid, which was confirmed to have an enhancing effect on glucose-dependent insulin secretion after intravenous glucose injection in SD rats.

CARBOXYLIC ACID COMPOUND

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, (2011/04/14)

To find a therapeutic agent and/or a preventive agent for diabetes mellitus or the like having excellent activity and safety. A compound represented by the following general formula (I), or a pharmacologically acceptable salt thereof. In the formula, X re

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