1202747-79-2Relevant academic research and scientific papers
Enantioselective synthesis of (+)-cephalostatin 1
Fortner, Kevin C.,Kato, Darryl,Tanaka, Yoshiki,Shair, Matthew D.
supporting information; experimental part, p. 275 - 280 (2010/03/25)
This Article describes an enantioselective synthesis of cephalostatin 1. Key steps of this synthesis are a unique methyl group selective allylic oxidation, directed C-H hydroxylation of a sterol at C12, Au(I)-catalyzed 5-endo-dig cyclization, and a kinetic spiroketalization.
