1202748-74-0

Basic information

• Product Name: (E)-2-hydroxy-N-(4-(2-hydroxy-5-iodobenzylideneamino)butyl)benzamide
• Synonyms: (E)-2-hydroxy-N-(4-(2-hydroxy-5-iodobenzylideneamino)butyl)benzamide
• CAS NO: 1202748-74-0
• Molecular Weight: 438.265
• Mol File: 1202748-74-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-2-hydroxy-N-(4-(2-hydroxy-5-iodobenzylideneamino)butyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-hydroxy-N-(4-(2-hydroxy-5-iodobenzylideneamino)butyl)benzamide(1202748-74-0)
• EPA Substance Registry System: (E)-2-hydroxy-N-(4-(2-hydroxy-5-iodobenzylideneamino)butyl)benzamide(1202748-74-0)

Safety Data

• Hazardous Substances Data: 1202748-74-0(Hazardous Substances Data)

Upstream product

• 1761-62-2 5-iodosalicyclaldehyde 

Relevant articles and documents

Synthesis, antibacterial activities and molecular docking studies of peptide and Schiff bases as targeted antibiotics

A series of peptide and Schiff bases (PSB) were synthesized by reacting salicylic acid, primary diamines with salicylaldehyde or its derivatives, and 40 of which were newly reported. The inhibitory activities against Escherichia coli β-ketoacyl-acyl carrier protein synthase III (ecKAS III) were investigated in vitro and molecular docking simulation also surveyed. Top 10 PSB compounds which posses both good inhibitory activity and well binding affinities were picked out, and their antibacterial activities against Gram-negative and Gram-positive bacterial strains were tested, expecting to exploit potent antibacterial agent with broad-spectrum antibiotics activity. The results demonstrate compound N-(3-(5-bromo-2-hydroxybenzylideneamino)propyl)-2-hydroxybenzamide (2d) can be as a potential antibiotics agent, displaying minimal inhibitory concentration values in the range of 0.39-3.13 μg/mL against various bacteria. Crown Copyright