1202769-93-4

Basic information

• Product Name: 3-Ethynyl-3-Hydroxy-1-Methylpyrrolidin-2-One
• Synonyms: 3-Ethynyl-3-Hydroxy-1-Methylpyrrolidin-2-One;3-Ethynyl-3-Hydroxy-1-Methylpyrrolidin-2-One(WXC01743)
• CAS NO: 1202769-93-4
• Molecular Formula: C₇H₉NO₂
• Molecular Weight: 139.15186
• Mol File: 1202769-93-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Ethynyl-3-Hydroxy-1-Methylpyrrolidin-2-One(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Ethynyl-3-Hydroxy-1-Methylpyrrolidin-2-One(1202769-93-4)
• EPA Substance Registry System: 3-Ethynyl-3-Hydroxy-1-Methylpyrrolidin-2-One(1202769-93-4)

Safety Data

• Hazardous Substances Data: 1202769-93-4(Hazardous Substances Data)

Upstream product

• 42599-26-8 1-methylpyrrolidine-2,3-dione 
• 4301-14-8 acetylenemagnesium bromide 

Relevant articles and documents

SMALL MOLECULE INHIBITORS OF NF-kB INDUCING KINASE

The present invention relates to compounds that inhibit NIK and pharmaceutical compositions comprising such compounds and methods of using the same. These compounds and pharmaceutical compositions are envisaged to be useful for preventing or treating diseases such as cancer (such as B-cell malignancies including leukemias, lymphomas and myeloma), inflammatory disorders, autoimmune disorders, immunodermatologic disorders such as palmoplantar pustulosis and hidradenitis suppurativa, and metabolic disorders such as obesity and diabetes.

ALKYNYL ALCOHOLS AS KINASE INHIBITORS

Selected compounds are effective for prophylaxis and treatment of inflammation and inflammatory disorders, such as NIK-mediated disorders. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, inflammation and the like.