120277-68-1

Basic information

• Product Name: Pyridine, 3-(chloromethyl)-2-methyl- (9CI)
• Synonyms: Pyridine, 3-(chloromethyl)-2-methyl- (9CI);3-(ChloroMethyl)-2-Methylpyridine;2-Methyl-3-(chloromethyl)pyridine
• CAS NO: 120277-68-1
• Molecular Formula: C₇H₈ClN
• Molecular Weight: 141.59812
• Product Categories: PYRIDINE;Aromatics, Heterocycles, Intermediates, Metabolites & Impurities
• Mol File: 120277-68-1.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 219.521ºC at 760 mmHg
• Flash Point: 107.422ºC
• Appearance: /
• Density: 1.118g/cm3
• Vapor Pressure: 0.176mmHg at 25°C
• Refractive Index: 1.527
• Storage Temp.: 2-8°C
• Solubility: Dichloromethane, Ethyl Acetate, Methanol
• CAS DataBase Reference: Pyridine, 3-(chloromethyl)-2-methyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 3-(chloromethyl)-2-methyl- (9CI)(120277-68-1)
• EPA Substance Registry System: Pyridine, 3-(chloromethyl)-2-methyl- (9CI)(120277-68-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 120277-68-1(Hazardous Substances Data)

Usage

Chemical Properties

Red Solid

Uses

3-(ChloroMethyl)-2-Methylpyridine is used in the preparation of Oxytocin antagonists and inhibitors of aggrecanase and MMP-13.

InChI:InChI=1/C7H8ClN/c1-6-7(5-8)3-2-4-9-6/h2-4H,5H2,1H3

Upstream product

• 56826-61-0 (2-methylpyridin-3-yl)methanol 
• 1721-26-2 ethyl 2-methyl nicotinate 
• 60032-57-7 2-methylnicotinaldehyde 
• 65719-09-7 methyl 2-methylnicotinate 

Downstream Products

• 1421928-16-6 C₂₇H₃₁ClN₂O₂ 
• 1421928-59-7 ethyl 2-(4-((2-methylpyridin-3-yl)methoxy)phenyl)acetate 
• 1421928-19-9 C₃₀H₃₁N₃O 
• 1421928-23-5 C₃₁H₃₂N₂O₂ 
• 1421928-47-3 C₃₀H₂₉ClN₂O₂ 
• 1421928-60-0 2-(4-((2-methylpyridin-3-yl)methoxy)phenyl)acetic acid hydrochloride 
• 1421928-11-1 C₂₉H₂₇ClN₂O₂ 
• 101166-73-8 (2-methylpyridin-3-yl)acetonitrile 
• 162045-26-3 1-(1-4-(1-(2-methyl-1-oxidopyridin-3-ylmethyl)piperidin-4-yloxyl-2-methoxybenzoyl)piperidin-4-yl)-1,4-dihydrobenz(d)(1,3)oxazin-2-one 

Relevant articles and documents

COMPOUNDS AND METHODS

The present invention relates to novel retinoid-related orphan receptor gamma (RORy) modulators and their use in the treatment of diseases mediated by RORy.

COMPOUNDS WHICH POTENTIATE THE AMPA RECEPTOR AND USES THEREOF IN MEDICINE

Compounds of formula (I) and salts thereof are provided: wherein n is 0, 1, 2 or 3; R1 is selected from phenyl and pyridyl, each of which is optionally substituted by one or two groups independently selected from C1-4alkyl and haloge

Novel tricyclic pyridyl carboxamides and derivatives thereof tocolytic oxytocin receptor antagonists

This invention provides novel substituted tricyclic pyridyl carboxamides which act as oxytocin receptor competitive antagonists, as well as methods of their manufacture, pharmaceutical compositions and methods of their use in treatment, inhibition, suppression or prevention of preterm labor, dysmenorrhea, endometritis, suppression of labor at term prior to caesarean delivery, and to facilitate antinatal transport to a medical facility. These compounds are also useful in enhancing fertility rates, enhancing survival rates and synchronizing estrus in farm animals; and may be useful in the prevention and treatment of disfunctions of the oxytocin system in the central nervous system including obsessive compulsive disorder (OCD) and neuropsychiatric disorders.