1202792-85-5

Basic information

• Product Name: (R,E)-methyl 2-hydroxy-3,3,7-trimethyl-2-((E)-styryl)oct-4-enoate
• Synonyms: (R,E)-methyl 2-hydroxy-3,3,7-trimethyl-2-((E)-styryl)oct-4-enoate
• CAS NO: 1202792-85-5
• Molecular Weight: 316.441
• Mol File: 1202792-85-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R,E)-methyl 2-hydroxy-3,3,7-trimethyl-2-((E)-styryl)oct-4-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: (R,E)-methyl 2-hydroxy-3,3,7-trimethyl-2-((E)-styryl)oct-4-enoate(1202792-85-5)
• EPA Substance Registry System: (R,E)-methyl 2-hydroxy-3,3,7-trimethyl-2-((E)-styryl)oct-4-enoate(1202792-85-5)

Safety Data

• Hazardous Substances Data: 1202792-85-5(Hazardous Substances Data)

Upstream product

• 202194-95-4 2,6-dimethylhept-2-en-4-ol 
• 119987-21-2 methyl α-styryl-α-diazoacetate 

Relevant articles and documents

Enantioselective C-C bond formation by rhodium-catalyzed tandem ylide formation/[2,3]-sigmatropic rearrangement between donor/acceptor carbenoids and allylic alcohols

The rhodium-catalyzed reaction of racemic allyl alcohols with methyl phenyldiazoacetate or methyl styryldiazoacetate results in a two-step process, an initial oxonium ylide formation followed by a [2,3]-sigmatropic rearrangement. This process competes favorably with the more conventional O-H insertion chemistry as long as donor/acceptor carbenoids and highly substituted allyl alcohols are used as substrates. When the reactions are catalyzed by Rh2(S-DOSP)4, tertiary R-hydroxycarboxylate derivatives with two adjacent quaternary centers are produced with high enantioselectivity (85-98% ee).