120286-67-1Relevant academic research and scientific papers
TOTAL SYNTHESIS OF (R)-(-)-β-CUPARENONE
Gharpure, Milind M.,Rao, A. S.
, p. 679 - 688 (2007/10/02)
(R)-(-)-β-Cuparenone has been synthesized from (S)-(+)-acid-2 obtained via resolution of the racemic acid.Two of the noteworthy steps are (a) repeated methylation of ester (+)-8 with LDA/MeI to furnish (+)-10 and (b) the reaction of 12, having two neopent
S-(-)-2-METHYL-2-PHENYLSUCCINIC ANHYDRIDE, A NOVEL RESOLVING REAGENT AND ITS APPLICATION TO RESOLUTION OF CIS-5-AMINO-4-PHENYL-1,3-DIOXANE
Gharpure, Milind M.,Rao, A. S.
, p. 1833 - 1840 (2007/10/02)
A new resolving reagent, (S)-(-)-2-methyl-2-phenylsuccinic anhydride (5) for the resolution of amines via covalent bond formation and its application to the resolution of aminodioxane (+/-)-(1) is described.The d.e. of the amides (8) has been determined b
