120287-30-1 Usage
General Description
8-bromo-6-nitroquinoline is a synthetic organic compound that is commonly used in research and laboratory settings as a building block for the synthesis of various other organic compounds. It is classified as a quinoline derivative, which is a heterocyclic compound containing a benzene ring fused to a pyridine ring. The compound is known for its distinctive red-brown color and is typically used in the production of dyes, pharmaceuticals, and agrochemicals. It has been studied for its potential as an anti-cancer agent and has shown promising activity in inhibiting the growth of cancer cells. However, its potential toxicological effects and environmental impacts continue to be areas of research and concern.
Check Digit Verification of cas no
The CAS Registry Mumber 120287-30-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,0,2,8 and 7 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 120287-30:
(8*1)+(7*2)+(6*0)+(5*2)+(4*8)+(3*7)+(2*3)+(1*0)=91
91 % 10 = 1
So 120287-30-1 is a valid CAS Registry Number.
120287-30-1Relevant articles and documents
INHIBITORS OF BRUTON'S TYROSINE KINASE
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Paragraph 0262; 0263, (2013/06/27)
This application discloses compounds according to generic Formula I: wherein the variables are defined as described herein, and which inhibit Btk. The compounds disclosed herein are useful to modulate the activity of Btk and treat diseases associated with
BROMINATION OF QUINOLINE DERIVATIVES WITH N-BROMOSUCCINIMIDE. ISOMERIC COMPOSITION OF THE BROMINATION PRODUCTS BY PMR AND GLC
Tochilkin, A. I.,Kovel'man, I. R.,Prokof'ev, E. P.,Gracheva, I. N.,Levinskii, M. V.
, p. 892 - 897 (2007/10/02)
The bromination of quinoline and substituted quinolines with N-bromosuccinimide in concentrated H2SO4 takes place exclusively in the homocyclic part.Bromo-substituted quinolines can be obtained by this method.The bromination products were identified by PMR spectroscopy.The differences among the mono-, di-, and trisubstituted (in the benzene ring) compounds were established on the basis of the type of spectrum of the protons of the homocyclic part of the molecule.The compositions of the reaction mixtures were studied by GLC.
