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methyl 2-(3-fluoro-4-methoxyphenyl)-1-methyl-1H-imidazole-5-carboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1202942-06-0 Structure
  • Basic information

    1. Product Name: methyl 2-(3-fluoro-4-methoxyphenyl)-1-methyl-1H-imidazole-5-carboxylate
    2. Synonyms: methyl 2-(3-fluoro-4-methoxyphenyl)-1-methyl-1H-imidazole-5-carboxylate
    3. CAS NO:1202942-06-0
    4. Molecular Formula:
    5. Molecular Weight: 264.256
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1202942-06-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: methyl 2-(3-fluoro-4-methoxyphenyl)-1-methyl-1H-imidazole-5-carboxylate(CAS DataBase Reference)
    10. NIST Chemistry Reference: methyl 2-(3-fluoro-4-methoxyphenyl)-1-methyl-1H-imidazole-5-carboxylate(1202942-06-0)
    11. EPA Substance Registry System: methyl 2-(3-fluoro-4-methoxyphenyl)-1-methyl-1H-imidazole-5-carboxylate(1202942-06-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1202942-06-0(Hazardous Substances Data)

1202942-06-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1202942-06-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,2,9,4 and 2 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1202942-06:
(9*1)+(8*2)+(7*0)+(6*2)+(5*9)+(4*4)+(3*2)+(2*0)+(1*6)=110
110 % 10 = 0
So 1202942-06-0 is a valid CAS Registry Number.

1202942-06-0Relevant articles and documents

Synthesis and structure-activity relationships of antitubercular 2-nitroimidazooxazines bearing heterocyclic side chains

Sutherland, Hamish S.,Blaser, Adrian,Kmentova, Iveta,Franzblau, Scott G.,Wan, Baojie,Wang, Yuehong,Ma, Zhenkun,Palmer, Brian D.,Denny, William A.,Thompson, Andrew M.

supporting information; experimental part, p. 855 - 866 (2010/06/15)

Recently described biphenyl analogues of the antituberculosis drug PA-824 displayed improved potencies against M. tuberculosis but were poorly soluble. Heterobiaryl analogues of these, in which the first phenyl ring was replaced with various 5-membered ring heterocycles, were prepared with the aim of identifying potent new candidates with improved aqueous solubility. The compounds were constructed by coupling the chiral 2-nitroimidazooxazine alcohol with various halomethyl-substituted arylheterocycles, by cycloadditions to a propargyl ether derivative of this alcohol, or by Suzuki couplings on haloheterocyclic methyl ether derivatives. The arylheterocyclic compounds were all more hydrophilic than their corresponding biphenyl analogues, and several showed solubility improvements. 1-Methylpyrazole, 1,3-linked-pyrazole, 2,4-linked-triazole, and tetrazole analogues had 3- to 7-fold higher MIC potencies against replicating M. tb than predicted by their lipophilicities. Two pyrazole analogues were >10-fold more efficacious than the parent drug in a mouse model of acute M. tb infection, and one displayed a 2-fold higher solubility. 2009 American Chemical Society.

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