120296-30-2

Basic information

• Product Name: Carbamic acid, [(1S)-1-formyl-2-(methylthio)ethyl]-, 1,1-dimethylethyl ester
• Synonyms: Carbamic acid, [(1S)-1-formyl-2-(methylthio)ethyl]-, 1,1-dimethylethyl ester;tert-butyl(S)-(1-(methylthio)-3-oxopropan-2-yl)carbamate;EOS-61964
• CAS NO: 120296-30-2
• Molecular Formula: C9H17NO3S
• Molecular Weight: 219.30118
• Product Categories: N-BOC
• Mol File: 120296-30-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 323.4±37.0 °C(Predicted)
• Appearance: /
• Density: 1.090±0.06 g/cm3(Predicted)
• PKA: 10.87±0.46(Predicted)
• CAS DataBase Reference: Carbamic acid, [(1S)-1-formyl-2-(methylthio)ethyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(1S)-1-formyl-2-(methylthio)ethyl]-, 1,1-dimethylethyl ester(120296-30-2)
• EPA Substance Registry System: Carbamic acid, [(1S)-1-formyl-2-(methylthio)ethyl]-, 1,1-dimethylethyl ester(120296-30-2)

Safety Data

• Hazardous Substances Data: 120296-30-2(Hazardous Substances Data)

Upstream product

• 172749-96-1 (S)-methyl 2-((tert-butoxycarbonyl)amino)-3-mercaptopropanoate 
• 112392-63-9 (S)-methyl 2-(tertbutoxycarbonylamino)-3-(methylthio)propanoate 

Relevant articles and documents

Total synthesis of (-)-eudistomins with an oxathiazepine ring. Part 1. Formation of the oxathiazepine ring system

Formation of the oxathiazepine ring in eudistomins 1 was investigated. Thiazolidinyl-β-carboline 5 was successfully transformed into thiaindoloquinolizidine 7, but attempted oxidative transformation of 7 to 1 was not successful. The oxidative cyclization of 1-substituted-2 hydroxy-β-carboline 24 with NCS or the acid-catalyzed cyclization of the corresponding 5-oxide 26 with TsOH gave oxathiazepine 25, which was readily converted to (+)-debromoeudistomin L (+)-lf. (-)-Debromoeudistomin L (-)-lf was prepared from N-hydroxytryptamine 11 and the D-cysteinal 30. The Royal Society of Chemistry 2000.