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120298-30-8

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  • 2(5H)-Furanone,3-[(13R)-13-[(2R,2'R,5R,5'R)-5'-[(1S,5S)-1,5-dihydroxyundecyl]octahydro[2,2'-bifuran]-5-yl]-13-hydroxytridecyl]-5-methyl-,(5S)-

    Cas No: 120298-30-8

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120298-30-8 Usage

General Description

Squamocin is a chemical compound found in the seeds of Annona muricata, also known as soursop or graviola. It belongs to a group of compounds called annonaceous acetogenins which are known for their cytotoxic and antitumor properties. Squamocin has been studied for its potential use in treating cancer due to its ability to inhibit the growth of cancer cells. Research has shown that squamocin is effective against various types of cancer cells, including breast, lung, and prostate cancer. However, more research is needed to understand its mechanism of action and potential side effects before it can be used as a treatment for cancer.

Check Digit Verification of cas no

The CAS Registry Mumber 120298-30-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,0,2,9 and 8 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 120298-30:
(8*1)+(7*2)+(6*0)+(5*2)+(4*9)+(3*8)+(2*3)+(1*0)=98
98 % 10 = 8
So 120298-30-8 is a valid CAS Registry Number.
InChI:InChI=1/C37H66O7/c1-3-4-5-15-19-30(38)20-17-22-32(40)34-24-26-36(44-34)35-25-23-33(43-35)31(39)21-16-13-11-9-7-6-8-10-12-14-18-29-27-28(2)42-37(29)41/h27-28,30-36,38-40H,3-26H2,1-2H3/t28-,30-,31+,32-,33+,34+,35+,36+/m0/s1

120298-30-8Upstream product

120298-30-8Relevant articles and documents

Total syntheses of squamocin A and squamocin D, bi-tetrahydrofuran acetogenins from Annonaceae

Emde, Ulrich,Koert, Ulrich

, p. 1889 - 1904 (2007/10/03)

The total syntheses of the Annonaceous acetogenins squamocin A and squamocin D have been achieved. The synthesis follows a modular strategy, wherein a left-side chain, the central bis-THF core and the right-side chain are assembled together. Key reactions are additions of organomagnesium compounds to bi-THF aldehydes. At the end of the synthesis the butenolide moiety was introduced. This modular synthetic approach should be useful for the synthesis of other related natural products as well as pharmacologically interesting analogs.

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