120331-99-9

Upstream product

• 768-03-6 Phenyl vinyl ketone 
• 21205-91-4 9-borabicyclo[3.3.1]nonane dimer 

Downstream Products

• 34733-55-6 2,3-dimethyl-1,4-diphenyl-butane-1,4-dione 
• 73893-85-3 (2R*,3S*)-2,3-dimethyl-1,4-diphenylbutane-1,4-dione 
• 6084-17-9 2-chloro-1-phenylpropan-1-one 
• 15982-59-9 2-methyl-1,4-diphenylbutane-1,4-dione 
• 34880-83-6 2,3-diethyl-1,4-diphenyl-1,4-butanedione 

Relevant academic research and scientific papers

Selective intermolecular oxidative cross-coupling of enolates

Selective intermolecular oxidative cross-coupling of enolates, which is a bond-forming reaction between carbanion equivalents, remains as an unsolved issue despite its potential utility for the direct synthesis of unsymmetrical 1,4-diones. The main difficulty derives from the unavoidable homo-coupling. Our strategy depends on the selective one-electron oxidation of one enolate to afford an electrophilic carbonyl α-radical species, followed by trapping with another enolate. The present study demonstrates the selective oxovanadium(V)-induced cross-coupling between boron and silyl enolates.

Oxovanadium(v)-induced diastereoselective oxidative homocoupling of boron enolates

Oxovanadium(v)-induced dl-selective oxidative coupling of (Z)-boron enolate was demonstrated to give the corresponding 2,3-disubstituted 1,4-diketone in a good yield. High selectivity (up to 94:6) was attained when the reaction was performed with VO(OPr-i)2Cl at -30 °C. The Royal Society of Chemistry 2014.