1203455-36-0

Basic information

• Product Name: (2S,3R)-3-benzyloxy-2-(2-oxopropyl)piperidine-1-carboxylic acid benzyl ester
• Synonyms: (2S,3R)-3-benzyloxy-2-(2-oxopropyl)piperidine-1-carboxylic acid benzyl ester
• CAS NO: 1203455-36-0
• Molecular Weight: 381.472
• Mol File: 1203455-36-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S,3R)-3-benzyloxy-2-(2-oxopropyl)piperidine-1-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3R)-3-benzyloxy-2-(2-oxopropyl)piperidine-1-carboxylic acid benzyl ester(1203455-36-0)
• EPA Substance Registry System: (2S,3R)-3-benzyloxy-2-(2-oxopropyl)piperidine-1-carboxylic acid benzyl ester(1203455-36-0)

Safety Data

• Hazardous Substances Data: 1203455-36-0(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 1203455-33-7 (2S,3R)-3-hydroxy-2-(2-oxopropyl)piperidine-1-carboxylic acid benzyl ester 
• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 

Downstream Products

• 1203455-38-2 (2S,3R)-3-benzyloxy-2-[2-oxo-3-(7-bromo-6-chloro-4-oxoquinazolin-3(4H)-yl)propyl]piperidine-1-carboxylic acid benzyl ester 
• 1203455-37-1 (2S,3R)-3-benzyloxy-2-[2-oxo-3-(4-oxoquinazolin-3(4H)-yl)propyl]piperidine-1-carboxylic acid benzyl ester 
• 27257-66-5 febrifugine dihydrochloride 
• 17395-31-2 (-)-halofuginone didydrobromide 

Relevant articles and documents

Stereoselective total synthesis of all the stereoisomers of (+)- and (?)-febrifugine and halofuginone

A convenient method for the total synthesis of all the stereoisomers of febrifugine and halofuginone using D-arabinose and L-arabinose as the key starting materials is reported. Apart from the inherent stereocenters in these pentose sugars, the method utilizes the selective hydrogenolysis of the anomeric O-benzyl group, stereoselective Grignard reaction and Wacker oxidation as the key steps to obtain the important precursors for the total synthesis.