1203653-17-1

Basic information

• Product Name: 4-((4-(1-cyanocyclopropylamino)-6-(6-methoxypyridin-3-yl)pyrido[3,2-d]pyrimidin-2-ylamino)methyl)benzenesulfonamide
• CAS NO: 1203653-17-1
• Molecular Weight: 502.556
• Mol File: 1203653-17-1.mol

Chemical Properties

• CAS DataBase Reference: 4-((4-(1-cyanocyclopropylamino)-6-(6-methoxypyridin-3-yl)pyrido[3,2-d]pyrimidin-2-ylamino)methyl)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-((4-(1-cyanocyclopropylamino)-6-(6-methoxypyridin-3-yl)pyrido[3,2-d]pyrimidin-2-ylamino)methyl)benzenesulfonamide(1203653-17-1)
• EPA Substance Registry System: 4-((4-(1-cyanocyclopropylamino)-6-(6-methoxypyridin-3-yl)pyrido[3,2-d]pyrimidin-2-ylamino)methyl)benzenesulfonamide(1203653-17-1)

Safety Data

• Hazardous Substances Data: 1203653-17-1(Hazardous Substances Data)

Upstream product

• 175358-01-7 3-amino-6-chloro-pyridine-2-carboxylic acid amide 
• 163105-89-3 2-methoxy-pyridine-5-boronic acid 
• 1036738-12-1 2,4,6-trichloropyrido[3,2-d]pyrimidine 
• 897360-38-2 6-chloropyrido[3,2-d]pyrimidine-2,4(1H,3H)-dione 

Relevant articles and documents

Optimization of pharmacokinetics through manipulation of physicochemical properties in a series of HCV inhibitors

A novel series of HCV replication inhibitors based on a pyrido[3,2-d]pyrimidine core were optimized for pharmacokinetics (PK) in rats. Several associations between physicochemical properties and PK were identified and exploited to guide the design of comp

2,4,6-TRISUBSTITUTED PYRIDO (3,2-d) PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS

Pyrido(3,2-d)pyrimidine derivatives represented by the structural formuia (Ia): wherein, R1, R2 and R3 are defined herein, pharmaceutical acceptable addition salts, stereochemical isomeric forms, N-oxides, solvates and pro