1203669-81-1Relevant articles and documents
HYDROPHOBICALLY ENHANCED AMINOGLYCOSIDES
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, (2011/08/04)
Hydrophobically enhanced aminoglycosides have been prepared and shown to be effective antibacterial agents. These agents may be used in the treatment or prevention of various bacterial infections. Methods of preparing these agents also permit facile synth
Synthesis and antibacterial activity of amphiphilic lysine-ligated neomycin B conjugates
Bera, Smritilekha,Zhanel, George G.,Schweizer, Frank
experimental part, p. 560 - 568 (2011/05/04)
Amphiphilic lysine-ligated neomycin B building blocks were prepared by reductive amination of a protected C5″-modified neomycin B-based aldehyde and side chain-unprotected lysine or lysine-containing peptides. It was demonstrated that a suitably protected