120369-42-8Relevant articles and documents
L -amino acid amides via dynamic kinetic resolution
Tessaro, Davide,Cerioli, Lorenzo,Servi, Stefano,Viani, Fiorenza,D'Arrigo, Paola
, p. 2333 - 2338 (2011/10/19)
Racemic natural and non-natural N-Boc-amino acid thioesters undergo enzyme-catalyzed ammoniolysis and aminolysis with concomitant base-catalyzed racemization of the non-transformed D-enantiomer with the formation of the corresponding L-amides in good yields and excellent enantiomeric purity all above 98% ee. This is the first example of a dynamic kinetic resolution of amino acid derivatives with amides formation. Copyright