120373-36-6 Usage
Uses
Unoprostane is a protectant against retinal degeneration in S334ter rhodopsin mutant rats. Neuroprotective agent.
General Description
Unoprostone (Rescula) is supplied as a 0.15% sterileophthalmic solution. Unoprostone is somewhat unusual inthat it is a docosanoid (22-carbon atom) PGF2α analog marketedas the isopropyl ester. The natural 15-position alcoholis oxidized to the ketone as would be expected to occur invivo. Cautions and side effects are similar to those givenpreviously.
Check Digit Verification of cas no
The CAS Registry Mumber 120373-36-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,0,3,7 and 3 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 120373-36:
(8*1)+(7*2)+(6*0)+(5*3)+(4*7)+(3*3)+(2*3)+(1*6)=86
86 % 10 = 6
So 120373-36-6 is a valid CAS Registry Number.
InChI:InChI=1/C22H38O5/c1-2-3-4-5-8-11-17(23)14-15-19-18(20(24)16-21(19)25)12-9-6-7-10-13-22(26)27/h6,9,18-21,24-25H,2-5,7-8,10-16H2,1H3,(H,26,27)/b9-6+/t18-,19-,20+,21-/m1/s1
120373-36-6Relevant articles and documents
Processes for the preparation of isomer free prostaglandins
-
Paragraph 0241; 0242, (2015/03/03)
Novel processes for the preparation of a compound of Formula I-2 substantially free of the 5,6-trans isomer: wherein R2, R3 and R4 are as defined in the specification are provided. Novel intermediates for the preparations of isomer free Prostaglandins and derivatives thereof are also provided.
Treatment of cataract with 15-keto-prostaglandin compounds
-
, (2008/06/13)
A compound for treatment of a cataract which is a 15-ketoprostaglandin compound.