120402-20-2

Upstream product

• 120402-19-9 2-benzyloxycarbonyl-2,3,4,4a,5,6,7,7a-octahydro-3-hydroxymethyl-5-methyl-4a-phenyl-cis-1H-cyclopentapyridine 
• 109988-66-1 5,5a,6,7,8,8a,9,9a-octahydro-8-methyl-8a-phenyl-1H,3H-oxazolo<3,4-a>cyclopentapyridin-3-one 
• 120402-06-4 4-hydroxyoxazolidin-2-one 
• 109988-58-1 N-<2-(1-phenylethenyl)-5-hexenyl>oxazolidine-2,4-dione 
• 109988-62-7 N-<2-(1-phenylethenyl)-5-hexenyl>-4-phenylthiooxazolidin-2-one 
• 945-93-7 ethyl (E)-3-phenylbut-2-enoate 
• 97580-25-1 ethyl 2-(1-phenylethenyl)-5-hexenoate 
• 97580-29-5 2-(1-phenylethenyl)-5-hexen-1-ol 

Downstream Products

• 120402-22-4 2,3,4,4a,5,6,7,7a-octahydro-2,5-dimethyl-4a-phenyl-1H-cis-cyclopentapyridine 

Relevant academic research and scientific papers

A Highly Diastereoselective Synthesis of cis-4a-Aryloctahydro-cyclopentapyridine Derivatives through Tandem Radical Cyclization of α-amino Radical Polyene Species

8a-Aryloxazolocyclopentapyridines (9a-c) were prepared via a route involving radical cyclization of α-acylamino radical polyene species generated by treatment of 4-phenylthiooxazolidin-2-ones (8a-c) with tri-n-butyltin hydride in the presence of azobisisobutyronitrile (AIBN).Conversion of 9a to cis-octahydro-2,5-dimethyl-4a-phenylcyclopentapyridine (19) was successfully achieved via a route involving ring cleavage of the oxazolidinone ring of 9a, oxidation of hydroxymethyl group, and decarbonylation.Keywords - radical cyclization; cyclopentapyridine; α-acylamino radical; α-amino radical-polyene; tandem radical cyclization; decarbonylation