1204085-53-9Relevant academic research and scientific papers
Antitumor antibiotic fostriecin covalently binds to cysteine-269 residue of protein phosphatase 2A catalytic subunit in mammalian cells
Takeuchi, Toshifumi,Takahashi, Noriyuki,Ishi, Kazutomo,Kusayanagi, Tomoe,Kuramochi, Kouji,Sugawara, Fumio
experimental part, p. 8113 - 8122 (2010/03/30)
Fostriecin is a phosphate monoester with excellent antitumor activity against mouse leukemia, and it is a potent inhibitor of protein phosphatase (PP) 2A. This compound has been predicted to covalently bind to the Cys269 residue of the PP2A catalytic subu
