120413-65-2Relevant academic research and scientific papers
Method for selectively preparing hydroquinone monoether compound or quinol compound (by machine translation)
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Paragraph 0040-0045; 0117-0119; 0154-0155, (2020/12/30)
The method comprises the following steps: taking an organic boric acid compound and a p-benzoquinone compound as a reaction raw material, under the action of a copper catalyst, selectively reacting to obtain a hydroquinone monoether compound or a quinol compound. Compared with the prior art, the method disclosed by the invention adopts a one-pot reaction, can selectively obtain two products through solvent control, is suitable for preparing various types of hydroquinone monoether compounds and quinol compounds, and has wide applicability. The substrate functional group is high in tolerance and wide in substrate range. The raw material and the catalyst are cheap and easily available, the reaction conditions are mild, the reaction solvent is green and environment-friendly, the post-treatment is simple, and the yield and purity of the product are high. The preparation method is convenient. The method is rapid and efficient, and has a good application prospect in drug molecule synthesis. (by machine translation)
Competitive Dienone-Phenol Type Rearrangements for the Regioselective Preparation of 2,4-Disubstituted-Naphth-1-ols
Dodge, Jeffrey A.,Chamberlin, A. Richard
, p. 4827 - 4830 (2007/10/02)
The regioselective preparation of 2,4-substituted-naphth-1-ols via a variant of the dienone-phenol rearrangement is described.
