1204142-58-4Relevant academic research and scientific papers
Synthesis of β-hydroxymalonates: the direct aldol addition of malonates to aldehydes in the presence of SiCl4 and i-Pr2EtN
Massa, Antonio,Scettri, Arrigo,Filosa, Rosanna,Capozzolo, Laura
, p. 7318 - 7321 (2009)
The direct aldol addition of malonates to aromatic, hetero-aromatic and unsaturated aldehydes leading to β-hydroxymalonates is described. The stability of these products, the trimethyl silyl protection of the hydroxyl group as well as the role of both SiC
