120419-72-9Relevant academic research and scientific papers
TiCl4-MEDIATED REACTIONS OF SILYL KETENE ACETALS DERIVED FROM N-METHYLEPHEDRINE ESTERS: ASYMMETRIC SYNTHESIS OF β-LACTAMS
Gennari, Cesare,Schimperna, Giuliana,Venturini, Isabella
, p. 4221 - 4232 (2007/10/02)
TiCl4 mediated addition of silyl ketene acetals derived from N-methylephedrine esters to various aldehydes and imines was used as the key-step in the enantio- and diastereo-controlled synthesis of β-lactams.Thus 3,4-trans and cis substituted-2-azetidinone
