120420-65-7Relevant academic research and scientific papers
Synthesis and Isomeric Conversions of Several 2-Substituted 1,4-Dihydro-4-oxo-3-quinolinecarboxylic Acid Derivatives
Kononov, L. I.,Veinberg, G. A.,Liepin'sh, E. E.,Dipan, I. V.,Sukhova, N. M.,Lukevits, E.
, p. 765 - 771 (2007/10/02)
Ethyl ester derivatives of 6- and 8-substituted 2-methyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids have been synthesized by treatment of the diethyl ester of acetylmalonic acid with 2- or 4-substituted anilines.Condensation of these newly synthesized quinolinecarboxylic acid derivatives with 4-nitrobenzaldehyde resulted in the formation of 6- and 8-substituted 2--1,4-dihydro-4-oxo-3-quinolinecarboxylic acids and ethyl esters of 6- and 8-substituted 2--4-acetoxy-3-quinolinecarboxylic acids.The tautomeric and conformational transformations of these newly synthesized compounds have also been investigated, using IR, NMR, and UV spectroscopy.
