120422-93-7

Usage

Uses

Used in Pharmaceutical Industry:
1H-Pyrazolo[4,3-c]pyridine,4-chloro-3-Methylis used as a building block for the synthesis of biologically active compounds, contributing to the development of new drugs. Its unique structure and functional groups make it a promising candidate for creating pharmaceutical agents with potential therapeutic applications.
Used in Agrochemical Industry:
1H-Pyrazolo[4,3-c]pyridine,4-chloro-3-Methylis used as a starting material for the development of new agrochemicals. Its chemical properties and reactivity can be harnessed to create compounds with pesticidal, herbicidal, or other agricultural applications, enhancing crop protection and yield.

Upstream product

• 120422-92-6 3-methylpyrazolo<4,3-c>pyridin-4(5H)-one 
• 134031-24-6 2,4-dichloro-3-pyridine Carboxaldehyde 
• 1246349-88-1 1-(2,4-dichloropyridin-3-yl)ethan-1-ol 
• 26452-80-2 2,4-dichloropyridine 
• 63523-62-6 6-chloro-4-hydrazino-3-methylisoxazolo<5,4-b>pyridine 
• 1246349-89-2 1-(2,4-dichloropyridin-3-yl)ethan-1-one 

Downstream Products

• 1246345-95-8 (4-chloro-benzyl)-(3-methyl-1H-pyrazolo[4,3-c]pyridin-4-yl)-amine 
• 1246346-53-1 (3-chloro-phenyl)-(3-methyl-1H-pyrazolo[4,3-c]pyridin-4-yl)-amine 
• 1246346-92-8 (1-benzyl-piperidin-4-yl)-(3-methyl-1H-pyrazolo[4,3-c]pyridin-4-yl)-amine 
• 1246346-91-7 N-(2,4-dimethoxybenzyl)-3-methyl-1H-pyrazolo[4,3-c]pyridin-4-amine 
• 1246346-86-0 N,N-dimethyl-N'-(3-methyl-1H-pyrazolo[4,3-c]pyridin-4-yl)-benzene-1,3-diamine 
• 1246347-14-7 4-(4-imidazol-1-yl-phenoxy)-3-methyl-1H-pyrazolo[4,3-c]pyridine 
• 1246350-46-8 4-chloro-3-methyl-1-trityl-1H-pyrazolo[4, 3-c]pyridine 
• 1246347-08-9 4-(cyclohexyloxy)-3-methyl-1H-pyrazolo[4,3-c]pyridine 
• 1246349-90-5 4-chloro-1-(4-methoxy-benzyl)-3-methyl-1H-pyrazolo[4,3-c]pyridine 
• 1367874-78-9 tert-butyl-4-(cyclohexyloxy)-3-methyl-1H-pyrazolo[4,3-c]pyridine-1-carboxylate 
• 1367874-79-0 tert-butyl-3-(bromomethyl)-4-(cyclohexyloxy)-1H-pyrazolo[4,3-c]pyridine-1-carboxylate 
• 1367874-80-3 [4-(cyclohexyloxy)-1H-pyrazolo[4,3-c]pyridin-3-yl]acetonitrile 
• 1367874-81-4 2-[4-(cyclohexyloxy)-1H-pyrazolo[4,3-c]pyridin-3-yl]ethanamine 
• 1367872-50-1 N-(2-(4-(cyclohexyloxy)-1H-pyrazolo[4,3-c]pyridin-3-yl)ethyl)cyclohexanecarboxamide 

Relevant academic research and scientific papers

PYRAZOLOPYRIDINES AS INHIBITORS OF THE KINASE LRRK2

The present invention relates to compounds of formula I, or pharmaceutically acceptable salts or esters thereof, (Formula I) wherein R1 is selected from: aryl; heteroaryl; -NHR3; fused aryl-C4-7 -heterocycloalkyl; -CONR4R5; - NHCOR6; -C3-7-cycloalkyl,-NR3R6; -OR3; OH; NR4R5; and alkyl optionally substituted with a substituent selected from R11 and a group A; wherein said aryl, heteroaryl, fused aryl-C4-7 -heterocycloalkyl and C4-7-heterocycloalkyi are each optionally substituted with one or more substituents selected from C1-6-alkyl, C3-7-cycloalkyl, heteroaryl, C4-7-heterocycloalkyl, aryl and a group A, and said C1-6- alkyl, C3-7-cycloalkyl, heteroaryl, C4-7-heterocycloalkyl, and aryl substituents are in turn each optionally substituted with one or more groups selected from R11 and a group A; R2 is selected from hydrogen, aryl, C1-6-alkyl, C2-6-alkenyl, C3-7-cycloalkyl, heteroaryl, heterocycloalkyi, fused aryl-C4-7-rheterocycloalkyl and halogen, wherein said C1-6-alkyl, C2-6-alkenyl, aryl, heteroaryl, fused aryl-C4-7 -heterocycloalkyl and C4-7 -heterocycloalkyl are each optionally substituted with one or more substituents selected from R11 and A. Further aspects relate to pharmaceutical compositions and therapeutic uses of said compounds

Photochemical rearrangements of 3-methyliscxazolopyridines

Irradiation in water-saturated ethyl ether of isoxazolopyridines 1a,e, beside the corresponding oxazolopyridines 2a,e, leads to N-methylcarboxamides 3a,e via 1-2 shift of the methyl group. The isoxazolopyridine 5, bearing a hydrazino group in 4-position, rearranges only to l-aminopyrazolopyridine 6.